Effects of Nicotinamide Riboside on Bioenergetics and Oxidative stress in Mild Cognitive Impairment/Alzheimer's Dementia

Mclean Hospital National Institute on Aging (NIA)

Purpose

To investigate the effects of exogenously administered nicotinamide riboside (NR) on brain energy metabolism, oxidative stress, and cognitive function in individuals with mild cognitive impairment (MCI) and mild Alzheimer’s dementia (AD).

Study Design

Open label, single group assignment

Dose

1000mg daily

Length of Intervention

12 weeks

Intrinsic Capacity

Cognition

Status

Not Yet Recruiting

Condition or Disease 

Mild Cognitive Impairment
Alzheimer’s Disease

Timeline estimations sourced on clinicaltrials.gov. All timing subject to change.

Alzheimer's, ClinicalANAD StaffAlzheimer's, Brain Health