Aberrant NAD+ metabolism underlies Zika virus-induced microcephaly

Reposted from Nature Metabolism

 

A study found that nicotinamide riboside (NR) supplementation reduced cell death and increased cortex thickness in Zika virus (ZIKV)-infected mouse brains. NR supplementation increased brain and body weight as well as improved survival in ZIKV-infected mice. This is the first study to show that Zika virus infection affected NAD+ metabolism.

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